DESCRIPTION:
This text aims to provide the general practitioner with a clear understanding of the objective, design, outcome and implication of the major trials of beta blockers as therapy for cardiovascular disease. A tabular summary of each trial accompanies an editorial comment highlighting major conclusions. Each trial is covered in a 2-page spread.
CONTENTS:
1. Secondary prevention: early intravenous intervention MIAMI, ISIS-1, TMI II (metroprolol).
2. Secondary prevention: long-term oral intervention.
3. Norwegian Timolol Study, BHAT (propranolol), Sotalol Study, Australian-Swedish trial (pindolol), EIS (oxprendolol), APSI.
4. Primary prevention: MRC Mild Hypertension (propranolol), IPPPSH (oxprenolol), HAPPHY (metoprolol), MAPHY (propranolol).
5. Primary prevention in the elderly: HEP, SHEP, STOP-Hypertension (pindolol), MRC trial in the elderly (atenolol).
