DESCRIPTION:
More than 160 authors_including more than 75 new contributors_lent their expertise to this sixth edition of The American Psychiatric Association Publishing Textbook of Psychopharmacology. Featuring 12 all-new chapters and fully aligned with the revised DSM-5-TR classification, this two-volume text offers an unrivaled, in-depth look at the rapidly evolving field of neuropsychopharmacology.
The opening chapters provide a whirlwind tour of the multiple disciplines that undergird the chapters to come, with topics extending from the principles of molecular biology and genomics to the rudiments of neuroimaging and personalized medicine in psychiatry. The main body of the Textbook features an examination of the medication classes that form the basis of psychopharmacological treatment. For each drug within a class, data are reviewed on history and discovery, preclinical and clinical pharmacology, pharmacokinetic parameters, mechanism of action, indications and efficacy, side effects and toxicology, and drug-drug interactions. The Textbook""s second volume focuses on psychopharmacological approaches to treatment of patients with major psychiatric disorders (e.g., mood and anxiety disorders, schizophrenia, substance use disorders) as well as patients in specific populations (e.g., adults with ADHD, pediatric patients). For each specific condition, patient population, or setting, chapters provide guidance on topics such as medication selection, combination and maintenance dosing regimens, side-effect monitoring and management, and optimization of treatment response. Closing this volume is an Appendix of Psychiatric Medications with key information on each of the agents covered in the Textbook, presented in a convenient tabular format.
Noteworthy additions to this textbook include chapters addressing the following topics:
- The potential roles of personalized medicine in psychiatry and of artificial intelligence and machine learning in psychopharmacology
- New medications with novel pharmacological mechanisms, including the neurosteroid antidepressant brexanolone and the atypical antipsychotic pimavanserin
- Use of investigational agents, such as psychedelics, in psychiatric treatment
- Treatment of alcohol use disorder, PTSD, OCD, and autism spectrum disorder
- Treatment of ADHD in adults
- Treatment of women in all life phases, including during pregnancy and the postpartum period
- Treatment of individuals with intellectual developmental disorder
With a level of detail not found in any other source, this new edition of The American Psychiatric Association Publishing Textbook of Psychopharmacology illuminates the path to effective evidence-based practice of psychopharmacology for novice and seasoned clinicians alike.
CONTENTS:
Part I: Principles of Pharmacology Chapter
1. Basic Principles of Molecular Biology and Genomics Chapter 2. Neurotransmitters Chapter 3. Genetics Chapter 4. Psychoneuroendocrinology Chapter 5. Brain--Immune System Interactions Chapter 6. Pharmacokinetics Chapter 7. Brain Imaging in Psychopharmacology
Part II: Classes of Psychiatric Treatments Antidepressants and Anxiolytics
Chapter 8. Monoamine Oxidase Inhibitors Chapter 9. Tricyclics Chapter 10. Fluoxetine Chapter 11. Sertraline Chapter 12. Paroxetine Chapter 13. Fluvoxamine Chapter 14. Citalopram Chapter 15. Trazodone and Nefazodone Chapter 16. Vortioxetine Chapter 17. Mirtazapine Chapter 18. Bupropion Chapter 19. Venlafaxine Chapter 20. Duloxetine, Milnacipran, and Levomilnacipran Chapter 21. Ketamine Chapter 22. Benzodiazepines Chapter 23. BuspironeAntipsychotics Chapter 24. Classic Antipsychotics Chapter 25. Clozapine Chapter 26. Olanzapine Chapter 27. Quetiapine Chapter 28. Risperidone and Paliperidone Chapter 29. Aripiprazole Chapter 30. Ziprasidone Chapter 31. Asenapine Chapter 32. Iloperidone Chapter 33. Lurasidone Chapter 34. Cariprazine Chapter 35. Drugs to Treat Extrapyramidal Side EffectsDrugs for Treatment of Bipolar Disorder Chapter 36. Lithium Chapter 37. Valproate Bowden Chapter 38. Carbamazepine Chapter 39. Gabapentin Chapter 40. Lamotrigine Chapter 41. TopiramateOther Agents Chapter 42. Agents for Cognitive Disorders Chapter 43. Sedative-Hypnotics Chapter 44. Psychostimulants and Wakefulness-Promoting Agents Chapter 45. Neurostimulation
Part III: Psychopharmacological Treatment Chapter
46. Treatment of Depression Chapter 47. Treatment of Bipolar Disorder Chapter 48. Treatment of Anxiety and Related Disorders Chapter 49. Treatment of Schizophrenia Chapter 50. Treatment of Substance-Related Disorders Chapter 51. Treatment of Personality Disorders Chapter 52. Treatment of Eating Disorders Chapter 53. Treatment of Insomnia Chapter 54. Treatment of Chronic Pain Chapter 55. Treatment of Child and Adolescent Disorders Chapter 56. Treatment During Late Life Chapter 57. Psychopharmacology During Pregnancy and Lactation Chapter 58. Treatment of Psychiatric Emergencies Chapter 59. Treatment of Agitation and Aggression in the Elderly
