DESCRIPTION:
This book describes the techniques, strategies, and drugs that have been demonstrated by at least one paper published in a peer-reviewed journal to significantly influence survival in patients with or at risk for acute kidney injury. Each chapter focuses on a specific intervention. The scope is accordingly wide, with coverage of topics as diverse as the type, timing, and dose of renal replacement therapy (RRT), anticoagulation and specific indications for RRT, perioperative hemodynamic optimization, fluid balance, diuretics, colloids, fenoldopam, terlipressin, N-acetylcysteine, and vasopressin. A variety of settings are considered, including critically ill patients, cardiac surgery, and hepatic and hematologic disorders. The topic selection was made using a democracy-based approach in which hundreds of specialists from dozens of countries expressed, via the web, whether they agreed with these topics and whether they used the techniques in their daily clinical practice. The clear text is supported by "how to do" sections and "key point" boxes that provide easily accessible practical information. The book will be of interest for a wide variety of specialists, including intensivists, nephrologists, emergency doctors, and anesthesiologists.
CONTENTS:
1. Acute Kidney Injury: The Plague of the New Millennium
2. Acute Kidney Injury: Definitions, Incidence, Diagnosis, and Outcome
3. Reducing Mortality in Acute Kidney Injury: The Democracy-Based Approach to Consensus
4. Continuous Renal Replacement Therapy Versus Intermittent Haemodialysis: Impact on Clinical Outcomes
5. May an "Early" Renal Replacement Therapy Improve Survival?
6. Increased Intensity of Renal Replacement Therapy to Reduce Mortality in Patients with Acute Kidney Injury
7. Citrate Anticoagulation to Reduce Mortality in Patients Needing Continuous Renal Replacement Therapy
8. Peri-angiography Hemofiltration to Reduce Mortality
9. Continuous Venovenous Hemofiltration to Reduce Mortality in Severely Burned Patients
10. Perioperative Hemodynamic Optimization to Reduce Acute Kidney Injury and Mortality in Surgical Patients
11. Furosemide by Continuous Infusion to Reduce Mortality in Patients with Acute Kidney Injury
12. Fenoldopam and Acute Kidney Injury: Is It Time to Turn the Page?
13. Vasopressin to Reduce Mortality in Patients with Septic Shock and Acute Kidney Injury
14. Terlipressin Reduces Mortality in Hepatorenal Syndrome
15. Albumin to Reduce Mortality in Cirrhotic Patients with Acute Kidney Injury
16. Extracorporeal Removal of Serum-Free Light Chains in Patients with Multiple Myeloma-Associated Acute Kidney Injury
17. Can Intravenous Human Immunoglobulins Reduce Mortality in Patients with (Septic) Acute Kidney Injury?
18. Fluid Overload May Increase Mortality in Patients with Acute Kidney Injury
19. Hydroxyethyl Starch, Acute Kidney Injury, and Mortality
20. Loop Diuretics and Mortality in Patients with Acute Kidney Injury
21. Reducing Mortality in Patients with Acute Kidney Injury: A Systematic Update
