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Neoplastic Diseases of the Blood integrates the history, epidemiology, pathology, pathophysiology, and therapeutics of modern neoplastic hematopathology. The book is divided into five major sections, with the first four covering the spectrum of hematologic neoplasia_ Chronic Leukemias and Related Disorders , Acute Leukemias, Myeloma and Related Disorders, and Lymphomas. The fifth section covers a variety of topics in supportive care. Now in its fifth edition, this classic and invaluable text brings together a team of internationally renowned experts and offers in-depth coverage of the complex interface between diagnosis and therapy. Chapters feature an accessible and easy-to-read layout and provide updates on the tremendous progress made in the last decade in the understanding of the nature of hematologic malignancies and their treatment. An authoritative and indispensable resource for students, trainees, and clinicians, this fifth edition is sure to distinguish itself as the definitive reference on this topic.

Part I: Chronic Leukemias and Related Disorders
1. A History of the Chronic Leukemias
2. Etiology and Epidemiology of Chronic Myeloid Leukemia
3. Pathology of the Chronic Myeloid Leukemias
4. Molecular Biology and Cytogenetics of Chronic Myeloid Leukemia
5. Diagnosis and Treatment of Chronic Myeloid Leukemia
6. Etiology and Epidemiology of CLL
7. Histopathology, Morphology, and Immunophenotyping of CLL
8. Molecular Biology and Cytogenetics of Chronic Lymphocytic Leukemia
9. Treatment of Chronic Lymphocytic Leukemia and Related Disorders
10. Hairy Cell Leukemia
11. The Pathogenesis, Diagnosis, and Treatment of Polycythemia Vera
12. Diagnosis and Treatment of Essential Thrombocythemia and Primary Myelofibrosis

Part II: Acute Leukemias
13. History of Acute Leukemia
14. The Etiology of Acute Leukemia
15. Epidemiology and Hereditary Aspects of Acute Leukemia
16. Classification of the Acute Leukemias: Cytochemical and Morphologic Considerations
17. Immunobiology of Acute Leukemia
18. Cytogenetics of Acute Leukemia
19. Diagnosis and Treatment of Childhood Acute Lymphoblastic Leukemia
20. Diagnosis and Treatment of Adult Acute Lymphoblastic Leukemia
21. Diagnosis and Treatment of Childhood Acute Myeloid Leukemia
22. Diagnosis and Treatment of Adult Acute Myeloid Leukemia Other Than Acute Promyelocytic Leukemia
23. Acute Promyelocytic Leukemia
24. Therapy-Related Acute Myelogenous Leukemia
25. The Myelodysplastic Syndromes

Part III: Myeloma and Related Diseases
26. History of Multiple Myeloma
27. Cytokines and Signal Transduction in Multiple Myeloma
28. Epidemiology of Multiple Myeloma
29. Immunoglobulins and Laboratory Recognition of Monoclonal Proteins
30. Cytogenetic Abnormalities in MGUS and Myeloma
31. Molecular Genetics of Myeloma
32. Prognosis and Staging of Multiple Myeloma
33. Diagnosis and Treatment of Multiple Myeloma
34. Complications and Special Presentations of Plasma Cell Myeloma
35. Waldenström""s Macroglobulinemia
36. Heavy-Chain Disease
37. Diagnosis and Therapy of Immunoglobulin Light Chain Amyloidosis (AL Amyloidosis)
38. Monoclonal Gammopathy of Undetermined Significance

Part IV: Lymphoma
39. Historical Landmarks in the Understanding of the Lymphomas
40. Genetics in Lymphomagenesis
41. Epidemiology and Hereditary Aspects of Hodgkin and Non-Hodgkin Lymphomas
42. Pathology of Non-Hodgkin and Hodgkin Lymphomas
43. Immunology of the Lymphomas
44. Cytogenetics of Lymphomas
45. Diagnosis and Treatment of Hodgkin""s Lymphoma
46. Radiotherapeutic Management of Lymphomas
47. Diagnosis and Treatment of Non-Hodgkin""s Lymphoma of Adults
48. Non-Hodgkin Lymphoma of Childhood
49. Lymphoma in Other Diseases

Part V: Supportive Care
50. Supportive Care for Patients with Leukemia: A Historical Perspective
51. Prevention of Infections in Patients with Hematological Malignancies
52. Evaluation and Management of Bacterial and Fungal Infections Occurring in Patients with a Hematological Malignancy: A 2011 Update
53. Viral Infections in Patients with Hematological Malignancies
54. Therapeutic Cytapheresis, Plasmapheresis, and Plasma Exchange in Neoplastic Diseases of the Blood
55. Red Cell Transfusions in Patients with Hematologic Malignancies
56. Platelet and Granulocyte Transfusion
57. Alternative Sources of Hematopoietic Stem Cells and Their Clinical Applications
58. HLA Typing in Support of Hematopoietic Cell Transplantation from Unrelated Donors
59. Special Care of Blood and Marrow Stem Transplant Patients
60. Hematopoietic Growth Factors in the Supportive Care and Treatment of Patients with Hematologic Neoplasms
61. Bleeding and Thrombosis in Hematologic Neoplasia
62. Psychological Aspects of Hematological Neoplasms

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