DESCRIPTION:
The percutaneous method of transluminal myocardial revascularization has roused enthusiasm in the field of cardiology because it is minimally invasive and relatively inexpensive. In his progressive new book, George Abela, a widely recognized pioneer in cardiology and lasers, has brought together the expertise of international leaders on the subject in this premier reference, Myocardial Revascularization: Novel Percutaneous Approaches. This resource provides interventional cardiologists, technical personnel and nurses in cardiac catheterization labs with the most current scholarly and clinical information available, including:
* A historical overview of myocardial revascularization (including the Vineberg procedure and the more recent TMR/PMR procedures)
* Biological responses and mechanisms of action in myocardial revascularization using mechanical, laser, ultrasound, and cryoenergy
* Current technology for the percutaneous method of the procedure
* Descriptions of other novel approaches including percutaneous in situ coronary venous arterialization
* Discussion of results from preliminary and advanced TMR/PMR in canine and human procedures
* Examination of various catheter navigation systems and potential adjunct gene therapies
* Myocyte transplantation to replenish the depleted myocardium
* Insights into the economics of these novel percutaneous techniques
CONTENTS:
PART I: BACKGROUND OF MYOCARDIAL REVASCULARIZATION TECHNIQUES.
Myocardial Revascularization: The Role of the Vineberg Operation and Related Procedures (O. Topaz).
Historical Perspectives and Development of Transmyocardial Revascularization (M. Cayton & M. Mirhoseini).
Clinical Efficacy and Experience with Transmyocardial Laser Revascularization (TMR) (K. Horvath).
PART II: BIOLOGICAL RESPONSES AND MECHANISMS OF ACTION OF MYOCARDIAL REVASCULARIZATION.
Angiogenesis vs. Arteriogenesis: Can Different Transmyocardial Revascularization Approaches be Distinguished (R. Virmani, et al.).
Revascularization versus Denervation: What are the Mechanisms of Symptom Relief? (G. Hughes & J. Lowe).
Potential Mechanisms of Myocardial Revascularization Techniques: Channels, Functional and Structural Remodeling, Angiogenesis, Denervation, or Placebo (E. Hage-Korban, et al.).
Biosense NOGA(TM): Percutaneous Laser Myocardial Revascularization and Gene Transfer (M. Foster, et al.).
PART III: CURRENT TECHNOLOGY FOR PERCUTANEOUS MYOCARDIAL REVASCULARIZATION.
Percutaneous Myocardial Revascularization (PMR): Indications and Clinical Experience (J. Eisenberg, et al.).
Novel Revascularization Strategies: PMR, TMR and Percutaneous in situ Coronary Venous Arterialization (W. Abernethy, et al.).
PART IV: OTHER METHODS OF MYOCARDINAL REVASCULARIZATION.
Transmyocardial and Percutaneous Myocardial Revascularization: Nonlaser Approaches (B. Kantor, et al.).
Cryoenergy-Induced Neovascularization for Myocardial Reperfusion: A Novel Alternative to Percutaneous Myocardial Revascularization (R. Gallo & M. Dubuc).
Ultrasonic Surgery: Mechanism of Action and Implications for Transmyocardial Revascularization (R. Verdaasdonk, et al.).
Left Ventricular Electromechanical Mapping As a Diagnostic Method (E. Perin, et al.). Percutaneous Gene Therapy for Myocardial Angiogenesis (S. Werns).
Myocardial Angiogenesis: Clinical Trial Results (T. Henry & C. Boisjolie).
The Coronary Veins as an Alternative Access for Gene Transfer and Angiogenesis by Selective Pressure-Regulated Retroperfusion (P. Boekstegers, et al.).
Percutaneous Intrapericardial Drug Delivery for Myocardial Angiogenesis (S. Waxman).
Cell Transplantation: Its Application in the Treatment of Cardiac Dysfunction and its Effect on Angiogenesis (M. Yao & R. Kloner).
Percutaneous Myocardial Revascularization: Financial Potential And Market Acceptance (T. Woodward, et al.).
