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MOLECULAR GENETICS OF CARDIAC ELECTROPHYSIOLOGY

MOLECULAR GENETICS OF CARDIAC ELECTROPHYSIOLOGY-9780792378297
  1. Autor:

    Berul

  2. Isbn:

    9780792378297

  3. Páginas:

    392

  4. Año:

    2000

  5. Edición:

    1

  6. Idioma:

    Ingles

  7. Disponibilidad:

    De 2 a 3 Semanas

Precio s/iva:

218.47 €

207,55  €
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DESCRIPTION:
The field of molecular genetics has rapidly expanded and is becoming increasingly important in the area of cardiac electrophysiology. The genetic basis of cardiac conduction disturbances and arrhythmogenesis is now recognized as a critical factor in disease pathology. Inherited structural and electrical heart diseases are being elucidated using molecular biological approaches, with differentiation of gene-specific diagnosis, prognostication, and therapeutics. Unique genetically-engineered animal models of hereditary arrhythmias and heart disease are being developed and utilized for detailed characterization of the cardiac conduction system.
The goal of this book is to provide the adult and pediatric cardiologist, electrophysiologist, geneticist, internist, pediatrician, and trainee with a comprehensive review and update of this new field involving the molecular genetics of cardiac electrophysiology.

CONTENTS:
Preface. 1. Overview: Genetics of Cardiac Electrophysiology
Section I: Experimental Investigation of Inherited Electrophysiological Disorders.
2. Single-Cell Electrophysiology & Ion Channelopathies
3. Animal Models of Inherited Electrophysiologic Diseases
4. Optical Mapping of Arrhythmias
5. Connexins and Conduction
Section II: Hereditary Arrhythmias.
6. Hereditary Supraventricular Tachycardias
7. Familial Atrial Fibrillation
8. The Molecular Cardiology of Heart Block
Section III: Ion Channel Mutations with Clinical Electrophysiologic Consequences.
9. Congenital Long QT Syndromes
10. Molecular Genetics of the Acquired Long QT Syndrome
11. Brugada Syndrome Genetics
Section IV: Inherited Cardiomyopathies with Arrhythmias.
12. Familial Hypertrophic Cardiomyopathy Genetics
13. Familial Dilated Cardiomyopathy
14. Glycogen Storage Diseases
15. Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
16. Cardiac Disease in Duchenne & Becker Muscular Dystrophies: The Dystrophinopathies
17. Myotonic Muscular Dystrophy Genetics and Cardiac Sequelae
Section V: Inherited Structural Heart Diseases Associated with Arrhythmias.
18. Genetic Causes of Atrial Septal Defects
19. Holt-Oram Syndrome and the TBX5 Transcription Factor in Cardiogenesis
20. Inherited Structural Heart Diseases Associated With Arrhythmias: Defects in Laterality
21. Marfan Syndrome and Related Disorders of Fibrillin
22. The Molecular Genetics of Conotruncal Defects



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