DESCRIPTION:
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care.
Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
CONTENTS:
1. Epidemiology of Renal Cell Carcinoma
2. Pathologic Considerations
3. Molecular Biology of Kidney Cancer
4. Biomarkers for Renal Cell Carcinoma
5. Genetic Heterogeneity of Kidney Cancer
6. The Metabolic Basis of Kidney Cancer
7. Renal Cell Carcinoma: Clinical Presentation, Staging, and Prognostic Factors
8. Hereditary Kidney Cancer Syndromes
9. Surgical Approaches to Early-Stage Renal Cell Carcinoma
10. Cytoreductive Nephrectomy
11. Metastasectomy
12. Thermal Ablative Techniques in Renal Cell Carcinoma
13. The Role of Radiation Therapy in Renal Cell Carcinoma
14. Adjuvant Systemic Therapy for Renal Cell Carcinoma
15. Cytokines in the Management of Advanced Renal Cell Cancer
16. Immune Checkpoint Inhibition in Renal Cell Carcinoma
17. Angiogenesis Inhibitor Therapy in Renal Cell Cancer
18. The Role of mTOR Inhibitors and PI3K Pathway Blockade in Renal Cell Cancer
19. Combinatorial and Sequential Targeted Therapy in Metastatic Renal Cell Carcinoma
20. Presurgical Therapy in Renal Cell Carcinoma
21. Variant Renal Carcinoma Histologies: Therapeutic Considerations
22. Toxicity Management of Renal Cell Cancer Patients on Targeted Therapies
23. Emerging Agents in Renal Cell Carcinoma
