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IMMUNOGENOMICS AND HUMAN DISEASE

IMMUNOGENOMICS AND HUMAN DISEASE-9780470034095
  1. Autor:

    Falus

  2. Isbn:

    9780470034095

  3. Páginas:

    548

  4. Año:

    2007

  5. Edición:

    1

  6. Idioma:

    Ingles

  7. Disponibilidad:

    De 2 a 3 Semanas

Precio s/iva:

164.30 €

156,09  €
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DESCRIPTION:
This book provides an overview of key conceptual and molecular technologies being deployed in immunogenomics, followed by detailed evaluations of the impact of genomics and systems biology on important areas such as cancer immunology, autoimmunity, allergy and the response to infection.

CONTENTS:
1. Genotyping methods and disease gene identification
2. Glycomics and the Sugar Code: Primer to their Structural Basis and Functionality
3. Proteomics in Clinical Research: Perspectives and Expectations
4. Chemical genomics: bridging the gap between novel targets and small molecule drug candidates. Contribution to immunology
5. Genomic and proteomic analysis of activated human monocytes
6. Bioinformatics as a problem of knowlege representation: applications to some aspects of immunoregulation
7. Immune responsiveness of human tumours
8. Chemokines regulate leukocyte trafficking and organ-specific metastasis
9. Towards a unified approach to new target discovery in breast cancer: combining the power of genomics, proteomics and immunology
10. Genomics and Functional Differences of Dendritic Cell Subsets
11. Systemic lupus erythematosus: new ideas for diagnosis and treatment
12. Immunogenetics of experimentally induced arthritis
13. Synovial activation in rheumatoid arthiritis
14. T cell epitope hierarchy in experimental autoimmune models
15. Gene-gene interactions in immunology as exemplified by studies on autoantibodies against 60 kDa heat-shock protein
16. Histamine genomics and metabolomics
17. The histamine H4 receptor: drug discovery in the post-genomic era
18. Application of microarray technology to bronchial asthma
19. Genomic investigation of asthma in human and animal models
20. Primary immunodeficiencies: genotype-phenotype correlations
21. Transcriptional profiling of dentritic cells in response to pathogens
22. Parallel biology: a systematic approach to drug target and biomarker discovery in chronic obstructive pulmonary disease
23. Mycobacterial granulomas: a genomic approach



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