DESCRIPTION:
This book focuses on the emerging non-invasive imaging technique of Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). FLIO reveals unique information on retinal diseases, ranging from age-related macular degeneration and vascular diseases to hereditary retinal dystrophies. Fluorescence lifetimes enable the evaluation of disease progression before irreversible structural changes occur. The image acquisition is suitable for diagnostic purposes and follow-up examinations to investigate the natural course of disease, and to monitor the effects of possible therapies.
This book fills the gap between available literature and gives state-of-the-art guidance on the principles of the FLIO technique, image acquisition, and data analysis. Written by a team of expert leaders within this field, this book will be relevant for scientists and clinicians with an interest in ophthalmoscopy.
CONTENTS:
1. Introduction
2. FLIO Technique and Principles
3. FLIO Historical Background
4. Fluorescence Lifetime Imaging Microscopy
5. The Fluorescence Lifetime Imaging Ophthalmoscope
6. Image Acquisition and Analysis
7. Fluorophores in the Eye
8. FLIO in the Healthy Eye
9. FLIO in Retinal Diseases
10. Age-Related Macular Degeneration
11. FLIO in Diabetic Retinopathy
12. Retinal Artery Occlusion
13. Central Serous Chorioretinopathy
14. Macular Telangiectasia Type 2
15. Hereditary Retinal Diseases: Stargardt, Choroideremia, Retinitis Pigmentosa
16. Macular Pigment
17. Fluorescence Lifetime Imaging Ophthalmoscopy in Alzheimer""s Disease
18. FLIO in Mouse Models
19. Discussion and Summary
Authors:
Prof. Martin S. Zinkernagel, MD PhD Department of Ophthalmology, University Hospital Bern, Switzerland - FEBO, ophthalmic surgeon
- current position: Consultant vitreoretinal specialist
- research focus: fluorescence lifetime imaging ophthalmoscopy, retinal imaging, mouse models of retinal diseases
Chantal Dysli, MD PhD Department of Ophthalmology, University Hospital Bern, Switzerland:
- research focus on fluorescence lifetime imaging ophthalmoscopy, retinal imaging
- currently residency in ophthalmology
