DESCRIPTION:
This book covers the management of all major renal diseases from an evidence-based and patient-centred approach. With contributions from leading international experts who have a real understanding of evidence-based medicine it provides recommendations on treatment regimens to adopt for individual patients that are most strongly supported by the evidence. The inclusion of the latest observational and epidemiological data, as well as randomized controlled trial evidence ensures that the book properly reflects the current state of evidence available for nephrological practice. It will be a useful aid to all clinicians, including those caring for transplant and pediatric patients, as it covers the major clinical questions encountered by nephrologists.
This reference is an invaluable source of evidence-based information distilled into guidance for clinical practice which will be welcomed by practitioners, trainees and associated health professionals.
CONTENTS:
PART 1 EPIDEMIOLOGY OF KIDNEY DISEASE AND EVIDENCE-BASED MEDICINE.
1. Epidemiology of chronic kidney disease.
2. Chronic disease surveillance and chronic kidney disease.
3. Risk factors for progression of chronic kidney disease.
4. Epidemiology and screening for chronic kidney disease.
5. Prediction of risk and prognosis: decision support for diagnosis and management of chronic kidney disease.
PART 2 ACUTE KIDNEY INJURY.
6. Definition, classification, and epidemiology of acute kidney injury.
7. Pre-renal failure and obstructive diseases.
8. Hepatorenal syndrome.
9. Acute tubular necrosis.
10. Radiocontrast nephropathy.
11. Miscellaneous etiologies of acute kidney injury.
12. Renal replacement therapy in acute kidney injury.
PART 3 PRIMARY GLOMERULONEPHRITIS.
13. Management of idiopathic nephrotic syndrome in adults: Minimal change disease and focal segmental glomerulosclerosis.
14. Membranous nephropathy.
15. IgA nephropathy in adults and children.
16. Membranoproliferative glomerulonephritis.
PART 4 SECONDARY DISEASE OF THE KIDNEY.
Hypertensive renal disease.
17. Hypertension: classification and diagnosis.
18. Management of essential hypertension.
19. Management of hypertension in chronic kidney disease.
20. Diagnosis and management of renovascular disease.
21. Diabetes mellitus.
22. Lupus nephritis.
23. Infection-related nephropathies.
24. Hepatitis B virus.
25. Infection-related nephropathies: Hepatitis C virus.
26. Polyomavirus-associated nephropathy.
Toxic nephropathies.
27. Toxic nephropathies: Nonsteroidal anti-inflammatory drugs.
28. Toxic nephropathies: Environmental agents and metals.
29. The kidney in pregnancy.
PART 5 CHRONIC KIDNEY DISEASE - CHRONIC RENAL FAILURE.
30 Progression of chronic kidney disease: diagnosis and management.
31. Treatment of anemia in chronic kidney disease, stage 3-5.
32. Dyslipidemia in chronic kidney disease.
33. Chronic kidney disease and hypertension.
34. Recognition and management of mineral and bone disorder of chronic kidney disease and end-stage renal disease.
35. Preparation for dialysis.
PART 6 CHRONIC KIDNEY DISEASE STAGE 5 - HEMODIALYSIS.
36. When to start dialysis and whether the first treatment should be an extracorporeal therapy or peritoneal dialysis.
37. Modalities of extracorporeal therapy: hemodialysis, hemofiltration and hemodiafiltration.
38. Dialysis delivery and adequacy.
39. General management of the hemodialysis patient.
40. Infections in hemodialysis.
41. Non-access-related nosocomial infections in hemodialysis.
42. Vascular access for hemodialysis.
PART 7 CHRONIC KIDNEY DISEASE STAGE 5 - PERITONEAL DIALYSIS.
43. Selection of peritoneal dialysis as renal replacement therapy.
44. Small solute clearances in peritoneal dialysis as renal replacement therapy.
45. Salt and water balance in peritoneal dialysis.
46. Impact of peritoneal dialysis solutions on outcomes.
47. Prevention and treatment of peritoneal dialysis-related infections.
PART 8 TRANSPLANT.
48. Evaluation and selection of the kidney transplant candidate.
49. Evaluation and selection of the living kidney donor.
50. Predictors of transplant outcomes.
51. The early course: induction, delayed function, and rejection.
52. Maintenance immunosuppression therapy.
53. Chronic allograft nephropathy.
PART 9 DISORDERS OF ELECTROLYTES (ACUTE AND CHRONIC).
54. Overview of electrolyte and acid-base disorders.
55. Hyponatremia.
56. Potassium disorders.
57. Metabolic evaluation and prevention of renal stone disease.
PART 10 PEDIATRICS.
Themes across renal disease and renal failure.
58. Growth, nutrition, and pubertal development.
59. Hypertension, cardiovascular disease, and lipid abnormalities in children with chronic kidney failure.
60. Bones across kidney disease and kidney failure.
61. Anemia.
Management of renal failure/transplants.
62. Renal transplantation.
63. Peritoneal dialysis in children.
64. Pediatric hemodialysis.
Specific pediatric renal disease.
65. Urinary tract infection, vesicoureteric reflux and urinary incontinence.
66. Epidemiology and general management of childhood idiopathic nephrotic syndrome.
67. Management of steroid-sensitive nephrotic syndrome.
68. Steroid-resistant nephrotic syndrome.
Other pediatric renal diseases .
69. Henoch-Schonlein nephritis and membranoproliferative glomerulonephristis.
70. Cystinosis.
