DESCRIPTION:
This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Covering the full range of common and rare nonneoplastic renal diseases, it incorporates the most recent scientific and technical knowledge in the field to provide a comprehensive overview of all key issues relevant to today""s practice. Richly illustrated and easy to use, Diagnostic Pathology: Kidney Diseases, fourth edition, is a visually stunning, one-stop resource for every practicing pathologist, nephrologist, resident, student, or fellow as an ideal day-to-day reference or as a reliable training resource.
Key Features:
- Provides a comprehensive source for key pathologies and clinical features of more than 265 kidney diseases
- Features two dozen new chapters on a variety of timely topics, including COVID-19 nephropathies, xenografts, artificial intelligence (AI), digital pathology analysis, harmonized nephropathology terminology, newly identified types of amyloidosis, common artifacts and pitfalls on kidney biopsy, vaccination-associated renal disease, crystal nephropathies, and much more
- Includes updates from the International Kidney and Monoclonal Gammopathy (IKMG) research group, the American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for IgG4-related disease, Banff Foundation for Allograft Pathology, and others
- Details updated genetic causes of nephrotic syndromes and antinephrin antibodies in podocytopathies_by the investigator who discovered it
- Discusses the newly identified variant IgG nephropathy and novel membranous autoantigens
- Contains chapters on techniques, including immunofluorescence on paraffin sections, C4d staining, and polyomavirus detection in tissue
- Contains more than 4,300 print and online images, including high-resolution photographs and histologic images, full-color medical illustrations, radiologic images, and more
- Employs consistently templated chapters, bulleted content, key facts, a variety of tables, annotated images, pertinent references, and an extensive index for quick, expert reference at the point of care
- Shares the expertise of internationally recognized authors who provide fresh perspectives on multiple topics, with a particular emphasis on practical information that directly assists in making and supporting a diagnosis
- Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud
CONTENTS:
SECTION 1: INTRODUCTION AND OVERVIEW
4 Introduction to Renal Pathology
24 Normal Kidney Structure
36 Normal Kidney Development
46 Kidney Biopsy Reports
48 Needle Biopsy: Evaluation for Adequacy
52 Harmonized Nephropathology Terminology and Reporting
54 Consensus Definitions of Light and Electron
58 Common Artifacts and Pitfalls
SECTION 2: GLOMERULAR DISEASES
PODOCYTOPATHIES
66 Minimal Change Disease (Diffuse Podocytopathy)
74 Classification of Focal Segmental Glomerulosclerosis
78 Etiologic Classification of Focal Segmental Glomerulosclerosis
80 Focal Segmental Glomerulosclerosis, Primary
88 Focal Segmental Glomerulosclerosis, Adaptive (Secondary)
94 Collapsing Glomerulopathy
MEMBRANOUS NEPHROPATHY AND VARIANTS
104 Introduction to Membranous Nephropathy
112 Etiologies of Membranous Nephropathy
114 Membranous Nephropathy Due to PLA2R1 Autoantibodies
120 Membranous Nephropathy Due to Non-PLA2R1 Autoantibodies
126 Membranous Nephropathy Associated With Systemic Disease
130 Membranous Nephropathy With Anti-TBM Antibodies
132 Podocyte Infolding Glomerulopathy
IGA-RELATED GLOMERULONEPHRITIDES
134 Overview of IgA-Related Glomerular Diseases
138 IgA Nephropathy
152 IgA Vasculitis (Henoch-Schönlein Purpura)
158 IgA Acute Glomerulonephritis Associated With
162 Hepatic Disease With IgA Deposition
SLE AND RELATED AUTOANTIBODYMEDIATED DISEASES
164 Systemic Lupus Erythematosus
182 Mixed Connective Tissue Disease
184 Idiopathic Nonlupus Full-House Nephropathy
186 Mixed Cryoglobulinemic Glomerulonephritis
ANTI-GBM DISEASES
192 Anti-GBM Glomerulonephritis
200 Atypical Anti-GBM Disease
RELATED GLOMERULONEPHRITIDES
204 Classification of MPGN and Complement-Related Diseases
210 Dense Deposit Disease
218 C3 Glomerulonephritis
226 C1q Nephropathy
232 C4 Glomerulopathy
234 Immune Complex Membranoproliferative Glomerulonephritis
MONOCLONAL IMMUNOGLOBULIN GLOMERULAR DISEASES
242 Introduction to Diseases With Monoclonal
246 Monoclonal Immunoglobulin Deposition Disease
254 Proliferative Glomerulonephritis With Monoclonal IgG Deposits
258 Membranous Nephropathy With Masked IgG-Kappa Deposits
262 Type I Cryoglobulinemic Glomerulonephritis
266 Waldenström Macroglobulinemia
268 Crystalglobulin Glomerulonephritis
270 Light Chain Crystalline Podocytopathy
AMYLOIDOSIS
272 Amyloidosis Classification
278 AL/AH Amyloidosis
284 AA Amyloidosis
288 AFib Amyloidosis
290 AGel Amyloidosis
292 ALECT2 Amyloidosis
294 AApoAI Amyloidosis
295 AApoAII Amyloidosis
296 AApoAIV Amyloidosis