DESCRIPTION:
Diagnosis and Management of Hypertrophic Cardiomyopathy is a unique, multi-authored compendium of information regarding the complexities of clinical and genetic diagnosis, natural history, and management of hypertrophic cardiomyopathy (HCM)_the most common and important of the genetic cardiovascular diseases_as well as related issues impacting the health of trained athletes.
Edited by Dr. Barry J. Maron, a world authority on HCM, and with major contributions from all of the international experts in this field, this book provides a single comprehensive source of information concerning HCM. Recent advances in the field are discussed, including the importance of left ventricular outflow tract obstruction, the use of implantable defibrillators for the prevention of sudden death in young people, definition of the genetic basis for HCM and its role in clinical diagnosis and risk stratification, the development of more precise strategies for assessing the level of risk for sudden death among all patients with HCM, and the evolution of invasive interventions for heart failure symptoms, such as surgical management and its alternatives (alcohol septal ablation and dual-chamber pacing).
CONTENTS:
1. Phenotypic Expression and Clinical Course of Hypertrophic Cardiomyopathy.
2. Genetic Mutations that Remodel the Heart.
3. Genetic Basis and Genotype-Phenotype Relationships in Familial Hypertrophic Cardiomyopathy.
4. Historical Perspective, Mechanism, and Clinical Significance of Left Ventricular Outflow Tract Obstruction in Hypertrophic Cardiomyopathy.
5. Hypertrophic Cardiomyopathy with Latent (Provocable) Obstruction: Pathophysiology and Management.
6. Pathophysiology and Clinical Consequences of Atrial Fibrillation in Hypertrophic Cardiomyopathy.
7. Other Modes of Disability or Death Including Stroke, and Treatment Strategies in Hypertrophic Cardiomyopathy.
8. Disturbed Vascular Control in Hypertrophic Cardiomyopathy: Mechanisms and Clinical Significance.
9. Clinical Significance of Diastolic Dysfunction and the Effect of Therapeutic Interventions.
10. Value of Exercise Testing in Assessing Clinical State and Prognosis in Hypertrophic Cardiomyopathy.
11. Pathophysiology and Significance of Myocardial Ischemia in Hypertrophic Cardiomyopathy.
12. Hypertrophic Cardiomyopathy in Japan: Clinical, Morphologic and Genetic Expression.
13. Prevalence, Prevention and Treatment of Infective Endocarditis in Hypertrophic Cardiomyopathy.
14. Pharmacologic Treatment of Symptomatic Hypertrophic Cardiomyopathy.
15. Obstructive Hypertrophic Cardiomyopathy: Results of Septal Myectomy.
16. US Perspectives on the Role of Dual-Chamber Pacing in Patients with Hypertrophic Cardiomyopathy.
17. Dual-Chamber Pacing for Hypertrophic Obstructive Cardiomyopathy.
18. Alcohol Septal Ablation.
19. Alcohol Septal Ablation in the Treatment of Hypertrophic Obstructive Cardiomyopathy: A Seven-Year Experience.
20. Role of Septal Ablation in a Surgical Center.
21. Molecular and Clinical Tools for Sudden Death Risk Assessment in Hypertrophic Cardiomyopathy.
21A. In Memorium: Asifa Quraishi.
22. Risk Stratification For Sudden Death in Hypertrophic Cardiomyopathy: Extreme Left Ventricular Hyptertrophy as a New Indicator of Risk.
23. Implantable Defibrillator for Prevention of Sudden Death in Hypertrophic Cardiomyopathy.
24. Hypertrophic Cardiomyopathy and Other Causes of Sudden Death in the Trained Athlete: An Electrophysiologist Perspective on the Management of Benign and Not So Benign Arrhythmias.
25. The Athlete""s Heart, the Athlete""s ECG, and Differential Diagnosis with HCM and Other Cardiomyopathies.
26. Importance of Congenital Coronary Artery Anomalies.
27. Arrhythmogenic Right Ventricular Cardiomyopathy and Hypertrophic Cardiomyopathy: Identification with the Italian Preparticipation Athlete Screening Program.
28. Cardiovascular Causes of Sudden Death, Preparticipation Screening, and Criteria for Disqualification in Young Athletes.
29.Sudden Death Due to Chest Blows (Commotio Cordis).
30. Naturally Occurring Animal Models of Cardiovascular Disease Causing Premature Death.
31. The Role of the Internet and Patient Support Groups for Those Living with Hypertrophic Cardiomyopathy.