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CHARNEY AND NESTLER"S NEUROBIOLOGY OF MENTAL ILLNESS

CHARNEY AND NESTLER"S NEUROBIOLOGY OF MENTAL ILLNESS-9780197640654
  1. Autor:

    Charney

  2. Isbn:

    9780197640654

  3. Páginas:

    1096

  4. Año:

    2025

  5. Edición:

    6

  6. Idioma:

    Ingles

  7. Disponibilidad:

    Próxima publicación

Precio s/iva:

197.12 €

187,26  €
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DESCRIPTION:
The Sixth Edition of Charney and Nestler""s Neurobiology of Mental Illness builds on previous editions of the book and reflects the continuing progress in reintegrating psychiatry into the mainstream of modern biomedical science. This reintegration remains a work in progress, based on the unique complexity of the brain and its diseases. Yet, the research tools that are transforming other branches of medicine-epidemiology, genetics, epigenetics, molecular and cell biology, imaging, and medicinal chemistry, along with fundamental advances in the neurosciences that make it possible to decipher cell types and their larger circuits to an unprecedented degree, are now at long last transforming psychiatry.

Collectively, the 75 chapters in this newly renovated textbook describe the developments in genetics and in molecular, cellular, and systems neuroscience that are breaking new ground in the diagnosis, treatment, and prevention of disabling psychiatric disorders.

In this updated edition, Section 1 focuses on the major methodological approaches to studying the biological basis of mental illness. Sections 2 through 8 each focus on a major class of mental illness, including schizophrenia, bipolar disorder, depression, anxiety and trauma disorders, substance use disorders, neurodegenerative disorders, and childhood psychiatry disorders.

The final section is a collection of essays that address what can be expected over the next decade in terms of improving psychiatric diagnosis, achieving a true precision approach to treating mental illness, along with new avenues of medication and non-medication therapies in the offing.

CONTENTS:
SECTION 1: EMERGING AND ESTABLISHED TECHNOLOGIES
1. Genetic Methodologies and Applications
2. Multiscale Network Approaches to Decode the Complexity of Common Human Diseases
3. The Role of the Epigenome in Brain Development, Function, and Disease
4. Methods for In Vivo Gene Manipulation
5. Application of Stem Cells to Understanding Psychiatric Disorders
6. Optogenetics and Related Technologies for Psychiatric Disease Research: Current Status and Challenges
7. Methods for In Vivo Circuit Analysis
8. Magnetic Resonance Methodologies
9. PET Brain Imaging Methodologies
10. Neuromodulation and Psychiatric Disorders

SECTION 2: SCHIZOPHRENIA
11. Diagnosis and Epidemiology of Schizophrenia
12. Genetics of Schizophrenia
13. Neuroimaging and Circuit Mechanisms of Schizophrenia
14. Animal and Cellular Models for the Study of Schizophrenia
15. Neural and Circuit Mechanisms of Schizophrenia
16. Glial-Immune Mechanisms of Schizophrenia: Animal and Human Studies
17. Translational Models for Psychotic Symptoms
18. Current Treatments for Schizophrenia
19. Novel Approaches for Treating Schizophrenia

SECTION 3: BIPOLAR DISORDER
20. Diagnosis and Epidemiology of Bipolar Disorder
21. Genetics of Bipolar Disorder
22. Neuroimaging and Circuit Mechanisms of Bipolar Disorder
23. Animal and Cellular Models for the Study of Bipolar Disorder
24. Molecular and Cellular Mechanisms of Bipolar Disorder: Animal and Human Studies
25. Current Treatments for Bipolar Disorder
26. Novel Approaches for Treating Bipolar Disorder

SECTION 4: DEPRESSION
27. Diagnosis and Epidemiology of Depression
28. Genetics of Depression
29. Neuroimaging and Circuit Mechanisms of Depression
30. Animal Models for the Study of Depression
31. Neurotrophic Mechanisms of Depression: Animal and Human Studies
32. Glial-Immune Mechanisms of Depression: Animal and Human Studies
33. Neuroendocrine Mechanisms of Depression: Animal and Human Studies
34. Current Treatments for Depression
35. Novel Approaches for Treating Depression

SECTION 5: ANXIETY AND TRAUMA-RELATED DISORDERS
36. Diagnosis and Epidemiology of Anxiety, Obsessive-Compulsive, and Trauma- and Other Stress-Related Disorders
37. Genetics of Anxiety and Trauma-Related Disorders
38. Neuroimaging and Circuit Mechanisms of Anxiety and Trauma-Related Disorders
39. Animal Models for the Study of Anxiety Disorders
40. Biological Mechanisms of Anxiety Disorders: Animal and Human Studies
41. Biological Mechanisms of Stress Resilience: Animal and Human Studies
42. Current Treatments for Anxiety and Trauma-Related Disorders
43. Novel Approaches for Treating Anxiety and Trauma-Related Disorders

SECTION 6: SUBSTANCE USE DISORDERS
44. Epidemiology of Substance Use Disorders
45. Genetics of Substance Use Disorders
46. Neuroimaging and Circuit Mechanisms of Substance Use Disorders
47. Animal Models for the Study of Substance Use Disorders
48. Cellular and Molecular Mechanisms of Substance Use Disorders: Animal and Human Studies
49. Brain Development and the Risk for Substance Use Disorders
50. Current Treatments for Substance Use Disorders
51. Novel Approaches for Treating Substance Use Disorders

SECTION 7: DEMENTIA
52. Diagnosis and Epidemiology of Dementia
53. Genetics of Alzheimer""s Disease, Parkinson""s Disease, and Lewy Body Dementia
54. Neuroimaging and Fluid Biomarkers of Alzheimer""s Disease
55. Molecular and Cellular Mechanisms of Alzheimer""s Disease: Animal and Human Studies
56. Molecular and Cellular Mechanisms of Primary Tauopathies: Animal and Human Studies
57. Neurobiology of Lewy Body Dementias: Animal and Human Studies
58. Current Treatments for Alzheimer""s Disease and Other Dementias
59. Novel Approaches for Treating Alzheimer""s Disease and Other Dementias

SECTION 8: PEDIATRIC PSYCHIATRIC DISORDERS
60. Diagnosis and Epidemiology of Pediatric Psychiatric Disorders
61. Genetics of Pediatric-Onset Psychiatric Disorders
62. Neuroimaging in Pediatric Psychiatric Disorders
63. Neurobiology of Autism Spectrum Disorders and Intellectual Disability: Animal and Human Studies
64. Neurobiology of Attention Deficit Hyperactivity Disorder: Animal and Human Studies
65. Neurobiology of Tic Disorders and Obsessive-Compulsive Disorder: Animal and Human Studies
66. Neurobiology of Eating Disorders: Animal and Human Studies
67. Current Treatments for Pediatric Psychiatric Disorders
68. Novel Approaches for Treating Pediatric Psychiatric Disorders

SECTION 9: FUTURE DIRECTIONS OF PSYCHIATRY
69. The Present and Future of Psychiatric Diagnoses
70. The NIMH Research Domain Criteria Project: Toward Precision Medicine in Psychiatry
71. Computational Psychiatry and the Bayesian Brain
72. Digital Assessments of Psychiatric Disorders
73. Digital Therapies of Psychiatric Disorders: Focus on Depression Symptoms
74. Psychedelic Drugs as Treatment Agents
75. Psychiatry""s Past Challenges and Future Opportunities



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