DESCRIPTION:
Discover the essential evidence-based handbook on the safe and effective prescribing of psychotropic agents in this comprehensive resource
Prescribing medications for patients suffering from mental illness is a challenging but essential component of clinical practice. Drug choice, dosage, and other considerations can have a critical impact on patient outcomes and long-term care. For years, The Maudsley Prescribing Guidelines have served as the indispensable evidence-based handbook for prescribing psychotropic medications. Now fully updated to reflect the latest evidence and practice, it will continue to serve a new generation of trainees and clinicians.
Readers of the fifteenth edition of The Maudsley Prescribing Guidelines will also find:
Becoming a Confident Child Psychological Therapist readers will also find:
- Analysis of all psychotropic drugs currently used in the US, UKA, Canada, Australia, New Zealand, and Japan Detailed discussion of topics including adverse effects, the ramifications of switching medication, special patient groups, and many more
- Fully up-to-date reference lists at the end of each chapter
The Maudsley Prescribing Guidelines is ideal for trainees looking to gain essential information on the rational, safe, and effective use of medications for patients with mental illness. Experienced clinicians will also find guidance on complex issues that they may not encounter regularly.
CONTENTS:
Chapter 1. Schizophrenia and related psychoses
Antipsychotic drugs
General introduction
General principles of prescribing
Antipsychotics - minimum effective doses
Quick reference for licensed maximum doses
Equivalent doses
High-dose antipsychotic medication: prescribing and monitoring
Combined antipsychotics (antipsychotic polypharmacy)
Antipsychotic prophylaxis
Negative symptoms
Monitoring
Relative adverse effects - a rough guide
Treatment algorithms for schizophrenia
First-generation antipsychotics - place in therapy
Nice guidelines for the treatment of schizophrenia
Antipsychotic response - to increase the dose, to switch, to add or just wait - what is the right move?
Acutely disturbed or violent behaviour
Antipsychotic depots/long-acting injections
Depot antipsychotics - summary of pharmacokinetics
Management of patients on long-term treatment with long-acting injectable antipsychotic medication
Aripiprazole long-acting injection
Olanzapine long-acting injection
Paliperidone palmitate long-acting injection
Risperidone long-acting injection
Penfluridol weekly
Electroconvulsive therapy and psychosis
Omega-3
fatty acid (fish oils) in schizophrenia
Alternative routes of administration
Stopping antipsychotics
Antipsychotic Adverse Effects
Extrapyramidal symptoms
Akathisia
Treatment of tardive dyskinesia
Antipsychotic-induced weight gain
Treatment of antipsychotic-induced weight gain
Neuroleptic malignant syndrome
Catatonia
ECG changes - QT prolongation
Effects of antipsychotic medications on plasma lipids
Diabetes and impaired glucose tolerance
Blood pressure changes with antipsychotics
Antipsychotic-associated hyponatraemia
Hyperprolactinaemia
Sexual dysfunction and antipsychotics
Pneumonia
Switching antipsychotics
Venous thromboembolism
Refractory Schizophrenia And Clozapine
Clozapine initiation schedules
Intramuscular clozapine
Optimising clozapine treatment
Alternatives to clozapine
Restarting clozapine after a break in treatment
Initiation of clozapine in the community
Clozapine Adverse Effects
Clozapine: common adverse effects
Clozapine: uncommon or unusual adverse effects
Clozapine: serious haematological adverse effects
Clozapine: serious cardiovascular adverse effects
Clozapine-induced hypersalivation
Clozapine-induced gastrointestinal hypomotility
Clozapine, neutropenia and lithium
Clozapine and chemotherapy
Genetic testing for clozapine treatment
Chapter 2. Bipolar disorder
Lithium
Valproate
Carbamazepine
Antipsychotic drugs in bipolar disorder
Antipsychotic long-acting injections in bipolar disorder
Physical monitoring for people with bipolar disorder
Treatment of acute mania or hypomania
Rapid-cycling bipolar affective disorder
Bipolar depression
Prophylaxis in bipolar disorder
Stopping lithium and mood stabilisers
Chapter 3. Depression and anxiety disorders
Introduction to depression
Antidepressants - general overview
Recognised minimum effective doses of antidepressants
Drug treatment of depression
Management of treatment-resistant depression - commonly used treatments
Management of treatment-resistant depression - other well-supported treatments
Treatment-resistant depression - other reported treatments
Ketamine
Psychotic depression
Switching antidepressants
Antidepressant withdrawal symptoms
Stopping antidepressants
Electroconvulsive therapy and psychotropic drugs
Psychostimulants in depression
Post-stroke depression
Antidepressant prophylaxis
Drug interactions with antidepressants
Cardiac effects of antidepressants - summary
Antidepressant-induced arrhythmia
Antidepressant-induced hyponatraemia
Antidepressants and hyperprolactinaemia
Antidepressants and diabetes mellitus
Antidepressants and sexual dysfunction
SSRIs and bleeding
St John""s wort
Antidepressants: relative adverse effects - a rough guide
Anxiety spectrum disorders
Benzodiazepines in the treatment of psychiatric disorders
Benzodiazepines, z-drugs and gabapentinoids: dependence, withdrawal effects and discontinuation
Benzodiazepines and disinhibition
Premenstrual syndrome
Chapter 4. Addictions and substance misuse
Introduction
Alcohol dependence
Opioid dependence
Nicotine and smoking cessation
Stimulant use disorder (SUD)
GHB and GBL dependence
Benzodiazepine misuse
Drug-induced excited state
Interactions between illicit drugs and prescribed psychotropic drugs
Drugs of misuse - a summary
Substance misuse in pregnancy
Gambling disorder
Chapter 5 Prescribing in children and adolescents
Principles of prescribing practice in childhood and adolescence
Depression in children and adolescents
Bipolar disorder in children and adolescents
Psychosis in children and adolescents
Anxiety disorders in children and adolescents 582 Obsessive compulsive disorder (OCD) and body dysmorphic disorder (BDD) in children and adolescents
Post-traumatic stress disorder (PTSD) in children and adolescents
Attention deficit hyperactivity disorder (ADHD) in children and adolescents
Autism spectrum disorder (ASD) in children and adolescents
Tics and Tourette""s syndrome in children and adolescents
Melatonin in the treatment of insomnia in children and adolescents
Rapid tranquillisation (RT) in children and adolescents
Doses of commonly used psychotropic drugs in children and adolescents
Chapter 6 Prescribing in older people
General principles in prescribing in older adults
Dementia
Safer prescribing for physical conditions in dementia
Management of behavioural and psychological symptoms of dementia (BPSD)
Management of inappropriate sexual behaviour in older adults
Depression in older adults
Covert administration of medicines within food and drink
A guide to medication doses of commonly used psychotropics in older adults
Chapter 7. Prescribing in pregnancy and breastfeeding
Drug choice in pregnancy
Drug choice in breastfeeding
Chapter 8. Prescribing in hepatic and renal impairment
Hepatic impairment
Renal impairment
Chapter 9 Drug treatment of other psychiatric conditions
Borderline personality disorder (BPD)
Eating disorders
Attention deficit hyperactivity disorder (ADHD) in adults
Chapter 10 Drug treatment of psychiatric symptoms occurring in the context of other conditions
Prescribing in human immunodeficiency virus (HIV)
Epilepsy
Learning disabilities
Huntington""s disease
Multiple sclerosis
Parkinson""s disease
Atrial fibrillation
Bariatric surgery
Menopause
Chapter 11. Pharmacokinetics
Plasma level monitoring of psychotropic drugs
Interpreting postmortem blood concentrations
Acting on clozapine plasma concentration results
Psychotropic drugs and cytochrome (CYP) function
Smoking and psychotropic drugs
Drug interactions with alcohol
Chapter 12 Other substances
Caffeine
Nicotine
Chapter 13. Psychotropic drugs in special conditions
Psychotropics in overdose
Driving and psychotropic medicines
Chapter 14. Prescribing psychotropics
Working towards adherence
Restarting psychotropic medications after a period of non-compliance
Relational aspects of prescribing practice
Prescribing drugs outside their licensed indications (`off-label"" prescribing)
The Mental Health Act in England and Wales
Site of administration of intramuscular injections
Chapter 15. Miscellany
Biochemical and haematological effects of psychotropics
Summary of psychiatric adverse effects of non-psychotropics
